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How are breast cancer subtypes related to the incidence of brain metastases, radiotherapy, and survival?

 Last Update: 2022-09-07
 Source: Internet
 Author: User

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Brain metastases (BRM) are the leading cause of morbidity and mortality in women with breast cancer

Despite the significant burden of symptomatic BRM on patients and the healthcare system, current guidelines do not recommend the use of neuroimaging for routine screening for BRM in women with early-stage or metastatic breast cancer (MBC)

In this population-based cohort study, the Population Health Management database of Ontario, Canada, held at ICES, was used to identify patients diagnosed with first-episode MBC between 2009 and 2018

RESULTS: Among 3916 MBC patients, 1215 (31.

BRM in patients with ERBB2-positive/HR-negative breast cancer (34.

The median (IQR) time from MBC diagnosis to brain radiotherapy ranged from 7.

Overall, the incidence and time to development of BRM varied by breast cancer subtype

Original source:

Wang XY, Rosen MN, Chehade R, et al.

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