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Hengrui SHR-1905 was approved as the third monoclonal antibody in the field of clinical asthma

 Last Update: 2021-05-21
 Source: Internet
 Author: User

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On May 12, the official website of CDE showed that Hengrui's Class 1 new drug SHR-1905 injection was approved for clinical use, and its indication is asthma.

At present, Hengrui has 2 monoclonal antibody drugs intended for asthma in the clinical stage, namely SHR-1819 targeting IL-4R and SHR-1703 targeting IL-5.

The fastest progress in the world is the TSLP-targeted monoclonal antibody Tezepelumab that Amgen and AstraZeneca collaborated on.

The curative effect of existing biological drugs is associated with increased eosinophil content, which is observed in 60% of patients with moderate to severe asthma.

TSLP is an epithelial cytokine produced in response to pro-inflammatory stimuli (such as lung allergens, viruses, and other pathogens).

According to the Insight database, AstraZeneca has currently carried out a phase III clinical trial of Tezepelumab for asthma in China.

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