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Hengrui Pharmaceuticals ERK Inhibitor Approved for Clinical

 Last Update: 2021-04-19
 Source: Internet
 Author: User

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On March 26, the CDE official website showed that Hengrui's application for clinical trial of extracellular regulatory protein kinase (ERK) inhibitors has been approved by the State Food and Drug Administration by default.

The MAPK signaling pathway is transmitted to multiple targets in the cell via RAS-RAF-MEK-ERK.

Previously, BPI-27336 from Betta Pharmaceuticals, HH2710 jointly developed by the Chinese Academy of Sciences and Shanghai Haihe, and Hutchison Whampoa's HMPL-295S1 were approved for clinical use.

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In addition, Deck Pharmaceuticals reached a global exclusive license agreement with AstraZeneca in November 2019, and obtained the right to jointly develop and commercialize the ERK1/2 inhibitor AZD0364 (ATG-017).

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