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With the rapid growth of the world’s population, it is necessary to increase grain output by another 50% by 2050 to fully meet demand.
The research group of Professor Guifang Jia from the School of Chemistry and Molecular Engineering of Peking University is dedicated to studying the molecular mechanism of RNA methylation modified N 6 -methyladenine (m 6 A) in regulating plant growth and development and stimulus response.
On July 22, the research group cooperated with the research group of Professor He Chuan of the University of Chicago and Academician Song Baoan of Guizhou University to jointly publish a report entitled " RNA demethylation increases the yield and biomass of rice and potato plants in field trials " in Nature Biotechnology .
In this study, FTO (RNA demethylase in mammals) was introduced into monocotyledonous rice and dicotyledonous potato to regulate m 6 A levels
This research has developed an innovative and universal epigenetic editing breeding technology for breeding high-yield and high-biomass varieties to increase grain production
FTO's Transformation of Rice Variety Nipponbare (Nipp)
FTO's Transformation of Potato Variety Eshu 3 (EM3)
Yu Qiong, postdoctoral fellow in Jia Guifang's research group (Crop RNA Modification Research), and Liu Shun, postdoctoral fellow in He Chuan's research group at the University of Chicago (Bioinformatics Analysis) are the co-first authors of the paper
