Heart disease research major new findings: injection of three proteins after myocardial infarction can protect the heart from damage!

Post-heart attack heart failure is caused by the irreversible loss of heart cells and is one of the leading causes of death and disability worldwide, according to the British Heart Foundation, one person is admitted to hospital for a heart attack every five minutes in the UK, and 64 million people worldwide suffer from heart failure, and there is currently no effective treatment

Scientists have discovered three proteins that can be injected immediately after a heart attack, and they have the potential to protect heart function

To systematically and unbiasedly identify previously unknown protein molecules with cardioprotective activity in vivo, led by Mauro Giacca, a professor of cardiovascular science at King's College London, researchers have developed an innovative technique: Cardiac FunSel, which is used to find proteins

Simply put, a barcode-labeled adeno-associated virus (AAV) vector library containing 1198 coded mouse secretion groups was used to screen for proteins

Mauro Giacca, professor of cardiovascular science at King's College London, said: "This is the first time that the therapeutic potential

Richard Francis, CEO of Forcefield Therapeutics, said: "Heart failure continues to have a devastating impact on public health and despite remarkable efforts in disease management, the long-term prognosis remains poor

Professor Ajay Shah, Director of the British Heart Foundation Centre for Research Excellence at King's College London, said: "This is early data, but if the results we see in mice can be confirmed in human trials, the potential for this treatment is very important and could revolutionize the treatment of patients at risk of heart failure

Professor James Leiper, Associate Director of Medicine at the British Heart Foundation, said: "Stopping injuries after heart injuries is a huge challenge for cardiology and this significant advance has the potential to lead to a new type of treatment that helps protect and reduce damage

Following a successful preclinical trial, the first human clinical trial

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