echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Blood System >  Haemophilia: Elevated endoglin levels in hemophilia patients are associated with angiogenesis-related Angiopoietin 2

     Haemophilia: Elevated endoglin levels in hemophilia patients are associated with angiogenesis-related Angiopoietin 2

    • Last Update: 2022-01-07
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    Hemophilia is a bleeding disease that occurs due to the lack of coagulation factors.
    The angiogenesis process is an important process in the pathophysiology of hemophilic arthropathy
    .
    Although very important progress has been made in the treatment of hemophilia today, the search for biomarkers that can predict the long-term increase in joint bleeding and hemophilia continues to determine the quality of life of hemophilia patients


    .


    Hemophilia is a bleeding disease that occurs due to the lack of coagulation factors.


    Table 1: Plasma levels of angiogenesis-related cell biomarkers in hemophilia patients and healthy controls

    Table 1: Plasma levels of angiogenesis-related cell biomarkers in hemophilia patients and healthy controls

    Table 2: mRNA expression of genes related to angiogenesis

    Table 2: mRNA expression of genes related to angiogenesis

    Compared with the control group, patients with hemophilia have significantly higher plasma ENG levels and angiogenesis markers


    .


    Compared with the control group, patients with hemophilia have significantly higher plasma ENG levels and angiogenesis markers


    Figure 1: The correlation between ENG and ANG-2 cytokines in hemophilia patients


    .


    Figure 1: The correlation between ENG and ANG-2 cytokines in hemophilia patients
    .


    Figure 2: Each gene in the hemophilia group doubled


    .


    Figure 2: Each gene in the hemophilia group doubled
    .


    Figure 3: Test results of AnxV binding to platelets


    .


    Figure 3: Test results of AnxV binding to platelets


    Original source:

    Original source:

    Karaman, K ,Celik, A ,Aytac, S , et al.
    Increased endoglin levels correlated with angiogenesis-associated angiopoietin-2 in haemophilia patients .
    Haemophilia .
    2021 ;27 :e747 –e753 .
    Https://doi.


    org/10.
    1111/ hae.
    14430

    Karaman, K ,Celik, A ,Aytac, S , et al.
    Increased endoglin levels correlated with angiogenesis-associated angiopoietin-2 in haemophilia patients .
    Haemophilia .
      2021 ;  27 :  e747 –  e753 .
      Https://doi.
    org/10.
    1111/ hae.
    14430 Karaman, K ,  Celik, A ,  Aytac, S , et al.
      Increased endoglin levels correlated with angiogenesis-associated angiopoietin-2 in haemophilia patients .
      Haemophilia .
      2021 ;  27 :  e747 –  e753.
      https://doi.
    org/10.
    1111/hae.
    14430 Leave a message here
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.