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Children with tumor survivors have a higher risk of subsequent primary tumor (SPNS), but the risk of developing SPNS into a specific digestive system over the age of 40 remains uncertain.
recently conducted a large-scale available world-wide queue study to determine the risk of subsequent specific digestive system SPNS in children with tumor survivors.
PanCareSurFup queue, which includes a total of 69,460 child tumor survivors in 12 European countries, looked at the standardized incidence of primary tumors in the follow-up digestive system (SIRS), absolute additional risk, and cumulative incidence of the population.
427 follow-up SPN events occurred among 413 survivors, including 214 cases of colon cancer, 62 cases of liver cancer, 48 cases of stomach cancer, 44 cases of pancreatic cancer and 59 cases of other tumors.
the risk of survivors of Wilmsoma (Wt, SIR=12.1) and Hodgkin's lymphoma (HL, SIR=7.31).
as WT survivors age, cumulative morbidity increases the fastest, reaching 7.4 percent at age 55 and 9.6 percent at age 60.
risk for gut SPNs, WT and HL survivors was still the highest, seven times higher than in the general population.
55, WT and HL survivors had a 2.3 percent risk of intestinal SPN.
risk of subsequent digestive tract tumors in childhood tumor survivors, particularly Wilms and Hodgkin's lymphoma survivors.
