GUT: Effects of postoperative colonoscopy review intervals on the risk of advanced lesions in patients with colonosis

Colonoscopy follow-up after pyriomic excision is essential, and researchers recently examined the effects of 1 review follow-up in 3 years or 2 follow-up in 1 and 3 years on the risk of advanced tumors (AN), including non-pictogram colorectal tumors (NP-crns).
The prospective multi-center randomized controlled trial was conducted at 11 Japanese medical centers, where participants underwent two rounds of baseline colonoscopy (one year apart) to ensure the removal of all tumor lesions, followed by 1 and 3 years follow-up endoscopy review groups (2 review groups) and only 3 years review groups (1 review group).
end point of this study is an AN event, defined as ≥10 mm low-level heterogeneity, high-level heterogeneity or immersive tumor lesions.
3,926 patients, with an average age of 57.3 years, 2,440 men (62%) and 2,166 completed follow-up visits, including 1,087 in 2 review groups and 1,079 in 1 review group.
29 AN incidents were discovered by a total of 28 people during the follow-up.
protocol analysis (701 in the 2 review group vs 763 in the 1 review group), the an incident rate was similar between the groups (1.7% vs 2.1%) and 1 review reached the non-inferior end point.
NP-CRN accounted for the majority of detected AN events (62%, 18/29), most of which were classified as horizontally diffused non-particle tumors (83%, 15/18).
study suggested that for patients with negative intestinal pulfusion results from 2 consecutive rounds of postoperative intestinal mirror review, the interval review time could be extended to 3 years and 1 time.