Gut bacteria may reduce the risk of cardiovascular disease　

, according to the results of a small clinical trial published online in Nature Medicine, increasing levels of certain gut bacteria may have beneficial effects on overweight or obese people. Gut bacteria Akkermansia muciniphila had lower levels in overweight or obese people with untreated type 2 diabetes or inflammatory bowel disease. The study suggests that the body can safely ingest the bacteria, which is associated with rising health levels.
to address the global evolution of cardiovascular metabolic diseases, scientists are increasingly concerned about interventions targeting the gut microbiome. Past studies based on animal models have shown that A. muciniphila is good for health, such as reducing obesity, poor glucose tolerance, insulin resistance, and liver fat accumulation.
a proof-of-concept study conducted by Patrice Cani and colleagues at the Catholic University of Leuven in Brussels, Belgium, showed that live or pasteurized A. muciniphila is safe and well-resistant to humans. A total of 32 volunteers who participated in the study used a placebo or A. muciniphila as a dietary supplement over a three-month period, the researchers said. The study eventually found the following changes in the intake of pasteurized bacterial preparations compared to those who took placebo: increased insulin sensitivity, decreased insulin levels, and improved cholesterol levels in the intestinal barrier and blood.
researchers concluded that further research is needed to determine whether the beneficial effects of pasteurizing A. muciniphila can be sustained for more than three months, and that larger controlled clinical trials are needed to assess efficacy. (Source: Tang Erdu, China Science Daily)