Green tea extract can improve cognitive function of brain

Green tea is recognized as having many positive effects on human health Now, for the first time, researchers at the University of Basel have shown that green tea extracts enhance cognitive function, especially working memory Swiss studies have found promising clinical implications for the treatment of cognitive disorders such as Alzheimer's Their results are published in the journal psychopharmacology In the past, the main components of green tea have been deeply studied in cancer research Recently, scientists have also been asked about the positive effects of drinks on the human brain Different studies link green tea to cognitive benefits However, the neural mechanism of the cognitive promotion of green tea is still unknown Better memory in a new study, led by Professor Christoph beglinger of the University Hospital of Basel and Professor Stefan Borgwardt of the psychiatry clinic, the team found that green tea extract improves the effective connection of the brain, meaning that this causal relationship affects one brain area to be applied to another Effective linking also improves actual cognitive ability: after ingestion of green tea extract, the subject tests of working memory tasks significantly improved The study asked healthy male volunteers to receive a soft drink containing a few grams of green tea extract before solving their working memory tasks Then, scientists used magnetic resonance imaging (MRI) to analyze the brain activity of the volunteers MRI showed increased connectivity between parietal and prefrontal cortex The discovery of these neurons is related to the active improvement of participants' task performance "Our results show that green tea can improve the short-term synaptic plasticity of the brain," Borgwardt said Clinical significance the results of this study suggest a promising clinical significance: modeling the effective connection between the frontal and parietal lobes in working memory processing may help to evaluate the efficacy of green tea, and be suitable for the treatment of neuropsychiatric diseases with cognitive impairment, such as Alzheimer's disease Abstract: green tea extract enhances parieto frontal connectivity during working memory processing Andr é Schmidt, Felix hammann, Bettina w? Lnerhanssen, Anne Christin Meyer Gerspach, J ü rgen drew, Christoph beglinger, Stefan borgward rational it has been proposed that green tea extract may have a beneficial impact on cognitive functioning, suggesting promising clinical implications However, the neural mechanisms underlying this putative cognitive enhancing effect of green tea extract still remain unknown 　　 Objectives 　　This study investigates whether the intake of green tea extract modulates effective brain connectivity during working memory processing and whether connectivity parameters are related to task performance 　　 Material and methods 　　Using a double-blind, counterbalanced, within-subject design, 12 healthy volunteers received a milk whey-based soft drink containing 27.5 g of green tea extract or a milk whey-based soft drink without green tea as control substance while undergoing functional magnetic resonance imaging Working memory effect on effective connectivity between frontal and parietal brain regions was evaluated using dynamic causal modeling 　　 Results 　　Green tea extract increased the working memory induced modulation of connectivity from the right superior parietal lobule to the middle frontal gyrus Notably, the magnitude of green tea induced increase in parieto-frontal connectivity positively correlated with improvement in task performance 　　 Conclusions 　　Our findings provide first evidence for the putative beneficial effect of green tea on cognitive functioning, in particular, on working memory processing at the neural system level by suggesting changes in short-term plasticity of parieto-frontal brain connections Modeling effective connectivity among frontal and parietal brain regions during working memory processing might help to assess the efficacy of green tea for the treatment of cognitive impairments in psychiatric disorders such as dementia.