Ginkgo biloba extract enhances the immune function of spleen and thymus in rats
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Last Update: 2016-01-04
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Source: Internet
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Author: User
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Recently, researchers from the school of basic medicine of Yunnan Dali University published a paper to study the effect of Ginkgo biloba extract (GBE) on the immune function of spleen and thymus in rats The results showed that Ginkgo biloba extract could enhance the immune function of thymus and spleen This paper was published in the 6th issue of the Journal of cell and molecular immunology in 2015 SD rats were given (40, 120, 360) mg / (kg · d) GBE by gavage, and the control group was set up at the same time After 28 days, the rats were killed by chloral hydrate anesthesia, and the quality indexes of thymus and spleen were measured; the proliferation and transformation of spleen lymphocytes induced by concanavalin A (Con A) were detected by MTT method; the phagocytic function of peritoneal macrophages was measured by neutral red test; the ultrastructural changes of spleen and thymus were observed by SEM The results showed that different doses of GBE could improve the organ quality index of thymus and spleen, but there was no significant difference between different dose groups; different doses of GBE could enhance the phagocytosis of macrophages and the proliferation of lymphocytes at all levels in the abdominal cavity of rats, and showed a certain dose-dependent The number of mature lymphocytes in spleen and thymus of rats treated with different doses of GBE was more than that of the control group.
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