Gilead announces new clinical research data on hepatitis B functional cure new drug GS-9688
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Last Update: 2020-06-07
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Source: Internet
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Author: User
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recently, Gilead, thegiant ofpharmaceutical(http:// released new clinical research data on the functional curethe new drug(http://Gs-9688( selgantolimod)About GS-9688
GS-9688 is an oral, selective toll-like receptor 8 (TLR8) small molecular agonistin a multicenter, randomized, double-blind Phase II study of 48 patients with chronic HBV who had achieved virological inhibition, GS-9688 (once-a week oral oraldrug(http://(OAVs) was well tolerated during extended administration and showed pharmacodynamic activity on dose dependenceThe clinical activity of GS-9688 was also assessed: 5% of patients treated with GS-9688 decreased in levels of hepatitis B surface antigen (HBsAg) or HBeE antigen (HBeAg) at the 24th week of treatmentThese data support ongoing GS-9688 research and new combinations designed to enable functional cure of HBVThe safety and efficacy of GS-9688, a research compound that has not been approved by the U.SFDA (http:// or any other regulatory agency
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