Genomic sequence analysis of the new coronavirus

February 3, Nature published a paper online describing the analysis of the genome sequence of 2019-nCov by Zhang Yongzhen, a professor at the Shanghai Clinical Center for Public Health and fudan University's School of Public Health. The virus genome was obtained from a patient who worked in a seafood market where the first patients appeared. Genomic analysis showed that the virus was closely related to a group of SARS-like coronavirus previously found in Bats in China.
2019-nCov, which recently appeared in Wuhan, has spread to other parts of China and several other countries, including the United States, Germany and Japan. The first patient was admitted to hospital on December 12, 2019, and an investigation found that a seafood market in Wuhan that also sold wild animals or a potential source of the outbreak.zhang Yongzhen,
, and others studied a 41-year-old male seafood market worker who was admitted to a hospital in Wuhan on December 26, 2019, showing symptoms of respiratory diseases, including fever, chest tightness and cough. A combined use of antibiotics, antiviral drugs and glucoticoids was used, but the patient showed respiratory failure and the condition did not improve after three days of treatment.
the authors sequenced the genome of bronch pipe vesicle irrigation lotions (pulmonary secretions) collected from patients. They identified a new type of virus and found that its genome was 89.1% similar to the SARS-like coronavirus found in bats.
authors say that while it is not possible to conclude from the analysis of individual patients that the coronavirus is the cause of the current outbreak, these findings have been confirmed by independent studies of other patients. The sequence information was published on the Virology website on January 10. (Source: Science Network Feng Lifei)
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