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His research was published Feb.
Moen's lab understands microbes in a way that only engineers can understand: systems of sensors, circuits and actuators
In some cases, actuators may act on information by moving toward specific proteins or attacking foreign invaders
The "kill switch activator" is meant to quell anxiety about the possible entry of genetically modified microbes into the environment
"But previous work was either too high or too low in activation at the basal level," and whenever he addressed that, "the bacteria mutated
Also, in some cases, the kill switch might not fire for days
Moen, for example, is interested in developing genetically engineered microbes to eat plastic as a way to deal with hazardous waste
To overcome these obstacles, the researchers inserted multiple death switches—up to four—into the microbial DNA
During the experiment, the researchers tested these microbes every day
"This is the best 'death switch' ever developed
These experiments have also been done in mice, but going forward, Morn wants to create a microbial "death switch" that could be used in soil -- perhaps to kill pathogens deadly to crops -- or even in the human gut Treatment of diseases in the Tao
The end result is for microbes to do what we want and then disappear
Journal Reference :
Austin G.