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    Home > Biochemistry News > Biotechnology News > Genetically engineered microorganisms with kill switches

    Genetically engineered microorganisms with kill switches

    • Last Update: 2022-03-07
    • Source: Internet
    • Author: User
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    His research was published Feb.


    Moen's lab understands microbes in a way that only engineers can understand: systems of sensors, circuits and actuators


    In some cases, actuators may act on information by moving toward specific proteins or attacking foreign invaders


    The "kill switch activator" is meant to quell anxiety about the possible entry of genetically modified microbes into the environment


    "But previous work was either too high or too low in activation at the basal level," and whenever he addressed that, "the bacteria mutated


    Also, in some cases, the kill switch might not fire for days


    Moen, for example, is interested in developing genetically engineered microbes to eat plastic as a way to deal with hazardous waste


    To overcome these obstacles, the researchers inserted multiple death switches—up to four—into the microbial DNA


    During the experiment, the researchers tested these microbes every day


    "This is the best 'death switch' ever developed


    These experiments have also been done in mice, but going forward, Morn wants to create a microbial "death switch" that could be used in soil -- perhaps to kill pathogens deadly to crops -- or even in the human gut Treatment of diseases in the Tao


    The end result is for microbes to do what we want and then disappear


    Journal Reference :

    1. Austin G.



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