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Genetic regulation of blood cells: proximity of genes to genetic changes plays an important role

 Last Update: 2021-09-30
 Source: Internet
 Author: User

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Therefore, the International eQTLGen Consortium has conducted a large-scale study to study how genetic variation affects the expression of genes in the blood

Determine the mechanism of the first menstrual period

Many cis and trans effects on gene expression provide many new methods to explain the molecular relationship between a wide range of traits and diseases

Professor Markus Scholz said: "These results greatly expand our knowledge of how gene expression in blood is regulated, far beyond the currently available databases, such as the world's largest database GTEx to date

Data from 7524 subjects and patients from the Leipzig University School of Medicine

The alliance was established in 2014 and includes 37 studies with a total of 31,684 subjects and patients

The alliance was established by researchers from the Institute of Medical Informatics, Statistics and Epidemiology (IMISE), and led by a team from the University of Groningen

Journal Reference :

Urmo Võsa, Annique Claringbould, Harm-Jan Westra, Marc Jan Bonder, Patrick Deelen, Biao Zeng, Holger Kirsten, Ashis Saha, Roman Kreuzhuber, Seyhan Yazar, Harm Brugge, Roy Oelen, Dylan H.

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