On July 23, Ding Yi's research group, associate professor of College of Animal Science and Technology of Huazhong Agricultural University and School of Veterinary Medicine, published the latest research results online in Hepatology
Hepatology Fatty liver is one of the common metabolic diseases in animals (such as cows, chickens, cats, etc.
In this study, mice were fed a high-fat diet, high-fat and high-cholesterol, established fatty liver and steatohepatitis models, and treated with gastrodin
Compared with the control group, the liver weight, liver and serum triglyceride and cholesterol content, serum alanine aminotransferase and aspartate aminotransferase activities of gastrodin-treated mice were significantly reduced, lipid accumulation in liver cells and inflammation The sexual response was significantly alleviated, and genes related to lipid accumulation, inflammation and fibrosis were significantly down-regulated
Gene enrichment analysis found that gastrodin mainly activates AMPK (adenylate activated protein kinase) pathway
This research was funded by the National Natural Science Foundation of China
Related paper information: https://doi.
https://doi.
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