Garlic extract can reduce the risk of gastric cancer death!

Recently, the price of pork has really gone up all the way It's almost catching up with beef It's become a pig with the same reputation as dou you, Jiang Youjun, Tang Gaozong and ping you Of course, there was a time when you were ruthless with 7 yuan of garlic Garlic is really tough If you eat some garlic at lunch, you will have a smell in your mouth in the afternoon Even a few meters around can become a no man's land But this garlic is also a knife mouth tofu heart, spicy stimulation, but also help us sterilization, antioxidant, and even cancer prevention function [1] Recently, Li Wenqing and you Weicheng of Peking University Cancer Hospital, who have been following Linqu for 22 years, have shown that three methods, namely, radical treatment of Helicobacter pylori, vitamin supplement and garlic supplement, can effectively reduce the risk of death of gastric cancer, with a reduction rate of 38%, 52% and 34%, respectively The study was published in BMJ [2] The number of deaths caused by gastric cancer every year can rank among the top three in all kinds of tumors, half of which occur in China Linqu, Shandong Province, is one of the regions with the highest mortality rate of gastric cancer in the world It is estimated that between 1980 and 1982, 55 or 19 people died of gastric cancer per 100000 men or women The high mortality rate of gastric cancer in Linqu is closely related to the local diet The main local food, sour pancakes, is made of corn flour fermented overnight and often contains the carcinogen aflatoxin According to statistics, daily consumption of sour pancakes is associated with a 30% increased risk of gastric cancer [4] In addition, people in Linqu are lack of selenium and vitamin C The lack of these two nutrients is also related to the high risk of gastric cancer [5,6] However, the proportion of vegetables and fruits in the diet, including garlic, seems to reduce the incidence rate of gastric cancer [4] Maybe we can prevent gastric cancer by adding vitamins and garlic For this reason, researchers carried out experiments in Linqu in 1995 to test the preventive effects of vitamin supplements, garlic supplements, and radical treatment of Helicobacter pylori on gastric cancer At this time, H pylori has just been listed as a grade 1 carcinogen by who [7] A total of 3365 people participated in the experiment 2258 H pylori positive participants were divided into 2 × 2 × 2 groups and received 2 weeks of radical treatment, 7.3 years of vitamin supplement and / or 7.3 years of garlic supplement The remaining 1107 H.pylori negative participants received the same vitamin supplement and / or garlic supplement in 2 × 2 groups Amoxicillin of 1G and omeprazole of 20mg were used twice a day for two weeks After the breath test, the patients were still positive, and the patients who did not clear Helicobacter pylori had another course of radical treatment The vitamin supplement was taken orally twice a day by the vitamin supplement, including 250mg vitamin C, 100 IU vitamin E and 37.5 μ g selenium, and 7.5mg β - carotene in the first six months Participants who took garlic supplements took them twice a day Each drug contains 200 mg of garlic extract and 1 mg of garlic oil obtained by steam distillation In the 15 year follow-up results published in 2010, [8] eradication of Helicobacter pylori showed significant preventive effect on gastric cancer Vitamin and garlic supplementation did not significantly reduce the incidence rate and mortality of gastric cancer, but also showed some good trends As a result, the researchers extended their follow-up to 22 years During a total follow-up of 22.3 years, 151 patients were diagnosed with gastric cancer and 94 died of gastric cancer Among them, 119 cases (79%) of gastric cancer diagnosis and 76 cases (81%) of gastric cancer death occurred in the baseline HP positive people In the prevention of gastric cancer, radical treatment of Helicobacter pylori and vitamin supplementation have shown good results, with an advantage ratio of 0.48 and 0.64, respectively But garlic supplements did not significantly reduce the incidence rate of gastric cancer In the prevention of gastric cancer death, the three methods have obvious effect Radical treatment of Helicobacter pylori, vitamin supplements and garlic supplements reduced the risk of gastric cancer death by 38%, 52% and 34%, respectively "These findings provide a potential opportunity for the prevention of gastric cancer, but further large-scale intervention trials are needed to confirm the good effect of vitamin and garlic supplementation, and to determine the treatment of Helicobacter pylori, as well as any risks that vitamin and garlic supplementation may bring," the researchers said It should be noted that the participants in this study are all from the high-risk rural areas of malnutrition and may not be able to be extended to the well nourished population I don't know if the 200 mg garlic extract and 1 mg garlic oil are equivalent to several cloves of garlic, but the hot "artificial meat" recently is more like the red meat it imitates or its raw bean products in terms of health If you want to get the first-hand scientific research information in time, you can't miss the blink of an eye, and the brand-new section - 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For a moment, there are a million possibilities References: 1  Nicastro H L， Ross S A， Milner J A。 Garlic and onions： their cancer prevention properties[J]。 Cancer prevention research， 2015， 8（3）： 181-189。 2  Li W Q， Zhang J Y， Ma J L， et al。 Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality： follow-up of a randomized intervention trial[J]。 bmj， 2019， 366： l5016。 3  Bray F， Ferlay J， Soerjomataram I， et al。 Global cancer statistics 2018： GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]。 CA： a cancer journal for clinicians， 2018， 68（6）： 394-424。 4  You W C， Blot W J， Chang Y S， et al。 Diet and high risk of stomach cancer in Shandong， China[J]。 Cancer research， 1988， 48（12）： 3518-3523。 5  You W， Zhang L， Gail M H， et al。 Gastric dysplasia and gastric cancer： Helicobacter pylori， serum vitamin C， and other risk factors[J]。 Journal of the National Cancer Institute， 2000， 92（19）： 1607-1612。 6  Zhang L， Blot W J， You W C， et al。 Serum micronutrients in relation to pre‐cancerous gastric lesions[J]。 International journal of cancer， 1994， 56（5）： 650-654。 7  Schistosomes I。 liver flukes and Helicobacter pylori。 IARC working group on the evaluation of carcinogenic risks to humans。 Lyon， 7–14 June 1994[J]。 IARC Monogr Eval Carcinog Risks Hum， 1994， 61： 1-241。 8  Ma J L， Zhang L， Brown L M， et al。 Fifteen-year effects of Helicobacter pylori， garlic， and vitamin treatments on gastric cancer incidence and mortality[J]。 Journal of the National Cancer Institute， 2012， 104（6）： 488-492。