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Editor in charge: Food Science
Introduction
Inflammatory bowel disease (IBD) is a recurrent inflammatory disease characterized by uncontrollable inflammation of the intestinal mucosa
Traditional IBD treatments include 5-aminosalicylic acid (5-ASA), corticosteroids (CS), Janus kinase inhibitors, anti-tumor necrosis factor-α (anti-TNF-α), antibodies, and surgery
Resveratrol and its derivatives have antioxidant, anti-tumor and anti-inflammatory functions.
Figure 1 Metabolism of resveratrol in the human body
Figure 2 Potentially related signaling pathways that resveratrol regulates IBD
TLR 2/4-mediated signaling pathwayTLRs are a class of receptors widely found in macrophages and neutrophils
Resveratrol and its metabolites are potential therapeutic agents for IBD
Resveratrol and its derivates improve inflammatory bowel disease by targeting gut microbiota and inflammatory signaling pathways
Ming Li, Ping Li, Rongxue Tang, Hui Lu *
State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China
*Corresponding author.
E-mail address: 402313318059@email.
Abstract
Inflammatory bowel disease (IBD) is a chronic inflammatory lesion of the intestine, mainly manifested by infiltration of intestinal inflammatory cells and imbalance of gut microbiota.
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