Front Neurosci: Star brain cells are associated with stuttering

February 13, 2021 /--- -- A study led by the University of California, Riverside, has found that astrogenic glial cells, which exist in the brain and are actively involved in brain function, may play an important role in stuttering.
A. Maguire, professor and chair of the Department of Psychiatry and Neuroscience at the UCR School of Medicine, said: "Our study shows that the use of libido can lead to increased synturological activity in stutterers.
mechanism for the role of ketones in stuttering appears to involve in part an increase in the metabolism or activity of star-shaped glial cells in the syroids.
(Photo: www.pixabay.com) the results of the study are published today in Frontiers in Neuroscience.
is a key component of the substrate nerve section, a group of nuclei known for promoting voluntary movement.
synths present in the frontal brain contain neuron activity associated with cognition, reward and coordination of movement.
stuttering is a spoken disease in children that causes speech disorders and is associated with high levels of the neurotransmitter dopamine.
can block the polypamine-acting litazone in the brain, thus preventing excessive dopamine activity.
is the world's most used prescription drug for schizophrenia and bipolar disorder for nearly three decades.
Maguire and Sheikh Bahaei have now found evidence that astrocytes in the sprite may reveal how lipe ketones reduce stuttering.
we know exactly how lipe ketones activate astrocytes in the sympospheric body," said Sheikh Bahaei, an expert on astronic glial cells.
" What we do know is that it activates astrogenic glial cells.
, the astrological glial cells release a signaling molecule that affects neurons in the synth by blocking their dopamine-like bodies.
In our future work, we hope to find this signaling molecule and better understand the exact role of astrogenic glial cells, which in turn could help us design drugs for astratic glial cells.
" Maguire and his team conducted a randomized, double-blind, placebo-controlled clinical trial of 10 adult subjects to observe the effects of lipester on brain metabolism.
at the start of the study, the 10 participants were assigned a separate reading assignment six weeks after taking lipe ketones (0.5-2.0 mg/day) or placebo pills.
then, each participant performs a positive electron emission fault scan or PET scan.
five subjects were given lipeone, while the other five were given a placebo.
based on scans conducted after active treatment, the participants in the Lipecozone treatment group showed higher glucose intake, or higher metabolism, in specific areas of the brain.
, Maguire and Sheikh Bahaei will work to learn more about what causes stuttering, the different types of stuttering, and why.
and provide targeted personalized treatments for stutterers.
(Bioon.com) Source: Star-shaped brain cells may linked to Stuttering Source: Frontiers in Neuroscience (2021). DOI: 10.3389/fnins.2021.598949 , ... ins.2021.598949/full