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Electrical signals tell the heart to contract, but when signals form spiral waves, they can lead to dangerous cardiac events such as tachycardia and fibrillation
Flavio Fenton, a professor in the School of Physics, said: "Clinicians knew decades ago that the heart can exhibit spiral wave electrical activity, and researchers have previously experimented
Studying the living hearts of heart transplant patients provides a rare window
The current work is part
Mapped hearts
To create conditions that produce spiral waves, the researchers performed a timed electric shock
"In this way, we can measure changes in light intensity, placing direct changes in calcium and heart cell voltage while seeing calcium and radio waves
Each heart needs a slightly different transplant, so researchers can study spiral wave dynamics
Work with clinicians
The team has been studying heart spiral waves for
Previously, the team had studied the hearts
Fenton said: "We are very fortunate to have this strong collaboration between Emory University and Georgia Tech to carry out these experiments
From a medical point of view, the study was also an eye-opener
"Based on what I saw clinically and what I read, I have a simple view of ventricular fibrillation, but in reality, looking directly at ventricular fibrillation through these experiments gives a different perspective on complexity and their dynamic changes," said Shahriar Iravanian, a cardiologist at Emory University who said
Harvard University A.
Researchers are continuing to work on heart transplants and hope to adapt experiments, not only for basic science, but also to improve treatment
"Due to patient instability and signal complexity, it is difficult to map ventricular fibrillation," said