FDA approves Gelesis company Plenity listing to help adults control weight

typically have a BMI of more than 25 that is considered overweight, while a BMI of more than 30 is considered obese, gelesis(http:// announcedthat the U.SFDA(http://approveits itsproduct(http://, which is used in combination with diet and exercise to help BMI control weight in adults at 25-40 kg/m2About The PlenityThis Company-developed Company-based Company," the Plenity product has a different innovative mechanism than previously approved weight-loss drugsPrevious weight-loss drugs have targeted neural circuits in the brain to suppress appetite or stimulate satietyPlenity is an oral water sol that cross-links two natural ingredients, modified cellulose and citric acidWhen The Plenity particles enter the stomach, they can quickly absorb water to form a three-dimensional structureIt's very similar in texture to the food it has chewed, and can be mixed with food, accounting for a quarter of the stomach's stomach capacity, causing a feeling of satiety, but not any caloriesAnd when this water sol runs to the large intestine, it is broken down by the enzyme part of the large intestine, thus losing the 3-dimensional structure of the water sol The released water can be reabsorbed by the large intestine, and the remaining cellulose material is drained 　　Plenity has been tested in five clinical trial (http:// In a recently completed randomized double-blind, placebo-controlled, multicenter key clinical study, 436 adults with a BMI between 27 and 40 received a six-month Plenity or placebo treatment results showed that 59 percent of adults who received Plenity's treatment lost more than 5 percent of their body weight And the average weight reduction in the Plenity group was significantly higher than that of the control group (-6.4% vs -4.4%, p.0007) People who received Plenity were twice as likely to lose more than 5 percent of the weight as the control group In subgroups with diabetes or prediabetes, those who had not received drug (http:// were six times more likely to lose more than 10 percent of their body weight than the control group