FD grants STRO-001 orphan drug for multiple myeloma
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Last Update: 2020-06-11
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Source: Internet
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Author: User
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recently, Sutro Biopharma(announced that the U.SFood andDrug(
FDA(
) has granted STRO-001 the right to treat multiple myeloma (MM) orphan drugsSTRO-001 is a potentially first-of-its-kind antibody drug, ADC, targeting CD47, a protein that is highly expressed in B-cell malignancies such as MMTHE STRO-001 UTILIZES SUTRO'S PROPRIETARY CELL-FREE PROTEIN
SYNTHETIC
(AND SITE-SPECIFIC CONJUGATE PLATFORM XPRESSCF PLUS), WHICH ENABLES THE PRECISE DESIGN AND RAPID EXPERIENCE OPTIMIZATION OF ADCS, DESIGNING AND MANUFACTURING HIGHLY OPTIMIZED SINGLE-MOLECULE SPECIES, RATHER THAN NON-PRECISE CONJUGATE ANTIBODY MIXTURES TYPICALLY PRODUCED ON CONVENTIONAL CELL MANUFACTURING PLATFORMSSTRO-001 is designed to target cancer cells directly and deliver cytotoxic agents, and the drug is currently being clinically developed for treatment of myeloma and B-cell lymphomaso far, Sutro has designed cytokine-based immuno-oncology therapies, antibody drug conjugate, and bispecific antibodies that target targets that have been clinically proven but currentstandard drug treatments are not effectiveSutro's platform accelerates the discovery and development of potentially first-in-one and best-in-class molecules by rapidly and systematically evaluating protein structure-active relationships to create optimizedproduct
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