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Tumor lymph node (LN) metastasis seriously affects the prognosis of treatment
.
Studies have shown that nanocarriers with a particle size of less than 50 nm can penetrate into LN metastases after intravenous administration
.
Recently, the Hai Medical School Professor Fang Chao team Jiaotong University in Nano-Micro Letters journal entitled to cover in the form of " Targeted Labeling Reagent Phthalocyanine for the Node Lymph Metastasis and Homing AN orthotopic Photothermal Therapy in Colorectal Tumor Model " papers
.
Researchers prepared trastuzumab-modified phthalocyanine micelles (T-MP, <50 nm) through the surfactant-stripping approach
.
Postdoctoral fellow of Shanghai Jiaotong University School of Basic Medicine Feng Haiyi and doctoral student Yuan Yihang are the first authors of the paper.
Professor Fang Chao of Shanghai Jiaotong University School of Medicine and Director Sun Peng of General Surgery Department of Shanghai Tongren Hospital are the corresponding authors of the paper
.