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Recently, an article circulated on the Internet for cancer patients and their families caused heated discussions.
The article called for "the country to set up a medical red line as soon as possible to curb bad medical behaviors in cancer treatment" and aroused extensive discussions among oncologists and patients
.
What is the significance of NGS sequencing for cancer patients? What role should the diagnosis and treatment guidelines play? How can hospitals and doctors better help patients and their families? Regarding some of the academic issues involved in the article, two experts from Jiahui International Cancer Center—Professor of Harvard Medical School, Director of Tumor Center of Shanghai Jiahui International Hospital, Professor Zhu Xiuxuan, Director of Clinical Research Institute of Shanghai Jiahui International Hospital, and University of Hamburg, Germany Professor Li Jun, the leader of the Department of Oncology Surgery of Shanghai Jiahui International Hospital, and the director of General Surgery and General Surgery of Shanghai Jiahui International Hospital, also shared his views with patients and colleagues
.
Whether to use NGS sequencing of tumor tissues should be determined after fully understanding the patient’s condition
Next Generation Sequencing (NGS) is relative to the traditional Sanger Sequencing, and is also called High-Throughput Sequencing
.
NGS is a very important technology platform in the entire oncology field.
Whether it is necessary to perform NGS sequencing for cancer patients needs to be considered from the three perspectives of speed, price, and practical operation after fully understanding the patient's situation
.
Single gene or small panel sequencing is very fast to detect some single targets, and the price is relatively cheap; for more comprehensive sequencing of multiple targets or tumor DNA, it will take longer and more expensive
Jiahui International Cancer Center adopts an international service model, so that patients and doctors have ample time to communicate and help better understand the condition
.
At the same time, the establishment of patient liaison specialists and case managers who can quickly assess the condition of the patient and timely triage, so that the oncologist can have an in-depth understanding of the patient's medical history before seeing the patient, and provide the patient with more valuable consultation and advice
Encourage doctors to systematically collect and judge the effects of treatment
For different cancers, various regions or countries in the world have formulated and followed different guidelines based on national conditions, drug approvals, and applicable populations
.
"The field of oncology is younger than other disciplines.
At present, as the strategic cooperative medical center of Massachusetts General Hospital and its cancer center in China, Jiahui International Tumor Center implements the International Tumor Board system and cooperates with Massachusetts General Hospital.
In-depth strategic cooperation, using its excellent overseas medical resources for experimental therapies and clinical research cooperation projects, will have the opportunity to benefit more Chinese cancer patients
.
Multidisciplinary Diagnosis and Treatment Mode (MDT) can assist in the comprehensive evaluation of cases
Some patients may not be able to distinguish the treatment departments corresponding to different tumors.
For example, for patients with gastrointestinal tumors, should they be treated in general surgery or medical oncology? Professor Zhu Xiuxuan said: "Digestive tract tumors include liver and gallbladder, pancreas, stomach, intestine, and esophagus.
Diagnosis and treatment are very complicated
.
Because of this, we need to uphold the concept of maximizing the benefits of patients, based on the multidisciplinary diagnosis and treatment model (MDT).
Professor Li Jun added: “In foreign countries, medical oncology became independent earlier.
For example, in Germany or the United Kingdom, if patients with gastrointestinal tumors require radiotherapy and chemotherapy before or after surgery, the selection of drugs and the formulation of plans must be based on MDT and The medical oncology department decided that it is impossible for the surgeon to perform this treatment alone
.
During the discussion, they often have different views on the radiotherapy and chemotherapy regimen and the appropriate timing of the operation.
Jiahui International Cancer Center provides international multidisciplinary discussion (MDT), integrating the concepts of individualized medicine, precision medicine, and rapid recovery into cancer diagnosis and treatment, so that patients can enjoy scientific and appropriate treatment plans and improve the survival of cancer patients Quality
.
The committee is jointly discussed by medical staff from various departments such as the Department of Oncology, Radiotherapy, Surgery, Pathology, Imaging, Nutrition, etc.
It includes tumor immunotherapy for various cancers, as well as tumors of the digestive system, breast cancer, hematological tumors, and lymphatics.
Under the premise of scientific development and continuous advancement of medicine, people still talk about cancerous discoloration, and the reasons behind it are worth thinking about in the industry
.
There is still much room for discussion and thinking in the industry in terms of raising awareness of tumor screening, standardized anti-cancer treatment, and all-round supportive treatment