Experts develop new coronavirus neutralizing antibodies that are expected to protect special populations

China News Online, May 15th (Chen Jing Shi Jiaqi) Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine in collaboration with Nankai University, Gaocheng Biology, Wuhan Virus Research Institute and other units jointly developed a new coronavirus neutralizing antibody P4A1-2A, Or have a positive effect on the prevention and treatment of the new coronavirus.

The first paper corresponding author, China Ke Xueyuan academician , former president of Nankai University Rao and academician said: "Over the years, in-depth study of structural biology has been playing an important role in the development of new antiviral drugs crown specific neutralizing antibodies.

The new type of coronavirus pneumonia is caused by coronavirus type 2 (SARS-CoV2), which looks like a sphere full of small "cauliflowers".

When the new crown epidemic broke out last year, Professor Sun Kun, a pediatric expert at Xinhua Hospital, and Huang Lisu, director of the infection department of the hospital, immediately discussed how to fight the epidemic scientifically with the top single-cell sequencing technology, and consider the issue of child protection.

According to the researchers, the antibody showed many advantages in subsequent preclinical trials.

"We hope that this neutralizing antibody can quickly benefit patients, including those who cannot benefit from the vaccine or cannot be vaccinated, such as young children, the elderly, and certain immune-compromised people.

As the co-corresponding author of the paper, Professor Sun Kun, Dean of Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine , said: "It is great to see the work of doctors in clinical research and to be able to efficiently cooperate and promote with the basic research team and the cross-transformation team.