Experimental study on the prevention of phlebitis caused by mannitol by external application of Polygonum cuspidatum
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Last Update: 2016-02-02
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Source: Internet
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Author: User
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Recently, neurosurgery researchers in the Affiliated Hospital of Zunyi Medical College published papers to explore the protective effect of Polygonum cuspidatum on mannitol induced phlebitis It is pointed out that Polygonum cuspidatum has a protective effect on vein and can prevent phlebitis This article was published in the 12th issue of Chongqing Medical Journal in 2015 Twenty four experimental rabbits were divided into three groups, eight in each group Mannitol infusion phlebitis model was established by external application of Polygonum cuspidatum and ethanol respectively, and the control group was blank The occurrence of phlebitis was observed by naked eyes Pathological samples were taken on the 5th day, and the degree of pathological damage was compared by light microscopy The incidence of phlebitis in the three groups was different, the incidence of phlebitis in the group of Polygonum cuspidatum was lower than that in the group of alcohol (P < 0.05); the degree of pathological injury in the three groups was different on the fifth day (P < 0.05); the degree of pathological injury in the group of Polygonum cuspidatum was different on the five aspects of vascular endothelial swelling, perivascular edema, inflammatory cell infiltration (P < 0.05); the degree of pathological injury in the three aspects of inflammatory cell infiltration, fibrous tissue proliferation and thrombosis It was lighter than that of ethanol group (P < 0.05).
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