Expanded vaccination is expected to reduce antibiotic use

A medical study published in the British journal Nature on the 29th, the United States team of scientists believe that pneumococcal and roulovirus can cause respiratory diseases and diarrhea, in response to these two vaccines, the expansion or introduction of their vaccination programs are expected to reduce the use of antibiotics in low- and middle-income children. The findings support giving priority to children in the global fight against drug resistance.Antibiotics are essentially a class of secondary metabolites produced by microorganisms (including bacteria, fungi, line-ups) or higher plants and animals in the course of life, with anti-pathogens or other active effects that interfere with the developmental function of other cells. However, bacteria are becoming more and more powerful in the game with antibiotics, and now, the resistance of pathogenic bacteria to antibiotics is a serious global public health problem, the most significant problem of drug resistance in low- and middle-income countries.With this in mind, Josephine Rauner, a scientist at the University of California, Berkeley, and colleagues analyzed data from large household surveys conducted in those countries to assess the effects of pneumococcal and rotisseria vaccines on antibiotic use in children under 5 years of age.The team found that 24.8 percent of respiratory infections treated with antibiotics and 21.6 percent of diarrhoeal infections treated with antibiotics were caused by pathogens sensitive to these vaccines. Children vaccinated against pneumococcal combinations or rotiss viruses were 8.7 per cent and 8.1 per cent less likely to develop antibiotic-treated respiratory and diarrhoeal infections than unvaccinated children.The researchers estimate that among children in low- and middle-income countries, pneumococcal and rotisseriosis vaccination programs currently prevent about 23.8 million antibiotic-treated respiratory infections and 13.6 million antibiotic-treated diarrhea episodes per year. If vaccination coverage is expanded in countries where these vaccines are used and children are introduced in countries where they are not used, it is possible to prevent an additional 40 million outbreaks of antibiotic-treated diseases.Editor-in-chiefvaccines and antibiotics, one is "anti" and the other is "cure". But the former's protective effect is long-term effective in a year or even years, in a sense, a million dollars. The misuse of antibiotics has become an important public health concern around the world, and treating antibiotic-resistant infections is becoming increasingly difficult and expensive, as agencies, including WHO, recommend making full use of existing vaccines and developing new ones to seriously address antibiotic resistance, and the scientific community needs to prioritize which new vaccines may have the greatest impact on antibiotic resistance and promote investment in those vaccines.
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