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    Home > Biochemistry News > Biotechnology News > Exosomes are pure and impure, and they are known at the first smell

    Exosomes are pure and impure, and they are known at the first smell

    • Last Update: 2022-09-14
    • Source: Internet
    • Author: User
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    Exosome-based intercellular communication spans all areas of


    Exosomes come from a complex environment, in which large amounts of lipoproteins, protein aggregates, and other non-vesicle components are often present


    In 2018, the International Society for Extracellular Vesicles (ISEV) brought together experts in the field to write and launch the Minimal Information for Studies of Extracellular Vesicles 2018 (MISEV2018


    Single exosome characterization


    Triton X-100 is a surfactant that cleaves the membrane structure of exosomes



    The company's self-developed membrane dye can realize the labeling of particles containing membrane structures in exosome samples, thereby realizing sample purity analysis


    Figure 5.


    Combined with SYTO 16 nucleic acid dye labeling and enzyme treatment strategies, the presence form and distribution characteristics of DNA molecules in exoFCM were analyzed in detail at the single particle level (Figure 7), and the DNA molecules carried by exosomes were mainly dsDNA.


    Figure 7.



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