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Excitatory postsynaptic protein PSD-93 plays an important role in the pathogenesis of depression

 Last Update: 2021-10-23
 Source: Internet
 Author: User

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The reporter learned from the University of Science and Technology of China that Zhou Jiangning’s research group used genetic manipulation of mice, combined with techniques such as behavior, patch clamp, chemical genetics, and in vivo optical fiber recording, and found that: The excitatory postsynaptic protein PSD-93 plays an important role in the pathogenesis of depression

Depression has become one of the major diseases affecting human life, but its pathogenesis is still unclear

Researchers first confirmed the co-localization of PSD-93 and CRH

This study revealed that PSD-93 of the hypothalamic paraventricular nucleus plays an important role in the pathogenesis of depression and explored possible mechanisms

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