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With the increasing use of endovascular therapy in the treatment of patients with acute ischemic stroke, baseline imaging has become more important for patients choosing treatmen.
In patients with acute ischemic stroke, CTP scans can reveal irreversibly damaged tissue (ie, the infarct core) and salvageable tissue (ie, the ischemic penumbra), which together constitute the total area of hypoperfusio.
Probabilistic classification of ischemic stroke regions has been proposed as an alternative to threshold-based classificatio.
Recently, a study published in European Radiology compared single parameter thresholds with multivariate probabilistic classification of ischemic stroke areas using CTP parametric maps generated by commercial methods (ISP), bSVD and nonlinear regression (NLR.
A total of 225 CTP datasets were included in this study, divided into 166 patients with successful recanalization and 59 patients with persistent occlusio.
Map baseline map (.
This study demonstrated that multivariate probability maps were superior to traditional CTP summary maps in assessing cerebral infarct lesions, as observed on follow-up unenhanced CT images obtained within 3 day.
Original source:
Daan Peerlings, Fasco van Ommen, Edwin Bennink, et a.
