Eur Radiol: What exactly is liver cell liver cancer without fast-forwarding and fast-out?

The qualitative diagnosis of hepatocellular liver cancer (HCC) does not require biopsy to a great extent, and the qualitative diagnosis can be achieved by relying solely on imaging characteristics.
and MRI are of great value for screening and diagnosis in high-risk populations of HCC.
HCC's blood supply characteristics, relying on the strengthening of the lesions - arterial period significantly strengthened, followed by enhanced serum can be diagnosed.
is an important feature of HCC diagnosis, which refers to the liver lesions in the valve vein period or delay period there is a reduction in the degree of strengthening than the arterial period.
, however, the degree of enhanced sequity of the HCC encountered was different.
in clinical work, radiologists evaluate the degree of tumor-liver substantive reinforcement contrast subjectively, which is not only affected by lesions and blood vessels, but also by the hemodynamics of the liver's substantive background.
recent studies have shown a correlation between HCC incidence and liver fatty degenerative lesions, such as non-alcoholic fatty liver disease (NAFLD).
the presence of fat degeneration, the liver's substantive background in ct density is reduced, which causes the typical clearing phenomenon on CT to disappear! At the same time, the dynamic enhancement MRI examination uses lipid pressure technology to reduce the effect of fat degeneration on the increase of lesions.
the use of CT and MRI to evaluate the presence of background fatty liver, HCC diagnosis and enhanced detection of signs of the detection of the effect? A paper published recently in Eur Radiol called Vanishing washout of hepatocellular carcinoma according to the presence of a paper on hepatic steatosis: "The presence of fatty livers affects the diagnostic value of enhanced profile and computer fault scanning (CT) and magnetic resonance imaging (MRI) for liver cell carcinoma (HCC).
the retrospective study included 566 patients with chronic liver disease who had liver tumor excisions (482 HCC and 84 non-HCC) between January 2016 and June 2018 to analyze arterial enhancement CT and MR images of patients.
Depending on the presence or failure of liver fat degeneration, patients are divided into fatty liver (n s 141) or non-fatty liver (n s 425) groups, and in pathological examination, liver fat degeneration is defined as the presence of lipid droplets in at least 5% of liver cells.
the presence of HCC-enhanced sequity between the two groups and the diagnostic performance of CT and MRI to HCC.
picture. The results of the study flow chart found that the incidence of HCC enhanced clearing in the fatty liver group was lower than in the non-fatty liver group (61.5% to 88.9%, p .lt;0.001), while on MRI, the two groups performed similarly (77.0% to 74.4%, p to 0.565).
on CT, the sensitivity of the fatty liver group to liver cancer diagnosis (53.3% vs. 80.0%, p -lt;0.001) and accuracy (53.9% vs. 80.9%, p.lt;0.001) were significantly lower than those of the non-fatty liver group.
, however, on MRI, there was no significant statistical difference between the groups (p.gt; 0.05).
. 59-year-old male patients with hepatocellular liver cancer and mild fatty liver, the signs of enhanced clearing on CT are blurred, the signs of enhanced clearing on MRI are blurred. In male patients with liver cancer and moderate fatty liver in 60 years of age, the signs of enhanced clearing on CT disappear, MR The results of this study show that liver fat degeneration will reduce the normal liver substantive background density, thus affecting the appearance of enhanced clearing signs, and then reduce the ability of CT to diagnose HCC, because of the use of lipid technology in arterial enhancement MRI scanning, the presence of liver fatty degeneration will not affect the diagnosis of HCC.
written later for radiologists, diagnosis of lesions is mostly dependent on the typical signs of lesions, like the liver cell liver cancer in the "fast-forward fast-out", which is one of the valuable signs of liver cell liver cancer diagnosis.
, however, in practice, if there is no "fast-forward fast-out" sign, then the diagnosis of liver cell liver cancer will be greatly reduced.
even if other signs are suspicious, a bold radiologist is more likely to have an atypical liver cancer and recommends a puncture biopsy.
this study analyzes the reasons for the disappearance of enhanced clear signs and identifies the factors affecting liver cell liver cancer in atypical imaging, which will solve the confusion of liver lesions diagnosis in clinical practice!