Eur Radiol: Is there a relationship between the indicator of amyosis and prognosis in patients with newly diagnosed glioblastoma?

Diffuse gliomas account for about 70% of primary malignant tumors in adults, while glioblastoma (GBM) is the most common glioma with a very high mortality rate.
no matter how much martial arts are on the whole, that is, a meal of operation like a tiger, back and forth to suffer, five-year survival rate of less than 10%.
of GBM patients is affected by a variety of factors, such as tumor size, location, suitability of patients receiving the best treatment.
Recent studies have found a correlation between amyopathy and extreme loss of palaeosis (TMT), which is a measure of the thickness of the crucum, and can be used as an indicator to predict the overall survival after brain metastasis or glioma surgery.
, however, there is no study using TMT to predict the survival of new GBM patients.
recently, a paper published in Eur Radiol called Prognostic relevance of temporal muscle thickness as marker of sarcopenia in patients with glioblastoma at diagnosis was designed to demonstrate the correlation between TMT and prognosis in patients with glioblastoma.
review of this study looked at patients who received methylated MGMT initiator IDH1-2 wild glioblastoma from January 1, 2015 to April 30, 2017, and who underwent a complete surgical excision and subsequent maintenance therapy for terpene.
last clinical or imaging follow-up date was September 3, 2019.
two-sided TMT was bilaterally measured on a standardized 3D MPRAGE image, using a 3-T MR scanner to capture the 3D MPRAGE image, with a collection time of no more than 2 days before surgery.
the TMT values of the median 25th and 75th percentage points were determined and patients subgrouped accordingly, and statistical analysis was used to evaluate the correlation between overall survival (OS) and TMT, gender, age, and ECOG performance status.
.TMT measurement method represents the graph In this study, the median OS was 20 months (range 3-51).
OS in patients with TMT≥8.4 mm (medium) did not show a statistically significant increase (Cox regression model: HR 1.34, 95% CI 0.68-2.63, p s 0.403).
same time, there was no statistical difference in OS between patients with TMT≥9.85 mm (fourth quarterile) and patients with TMT≤7 mm (first quarterile).
statistical analysis confirmed that there was a significant correlation between TMT and gender (p - 0.0186), but there was no statistical correlation between age (p s 0.642) and performance status (p s 0.3982).
in a homogeneity queue newly diagnosed with glioblastoma, TMT was independent of the patient's prognosis, age, or ECOG status.