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    Home > Active Ingredient News > Blood System > Eur Radiol: How to evaluate the structure and heterogeneity of multiple myeloma?

    Eur Radiol: How to evaluate the structure and heterogeneity of multiple myeloma?

    • Last Update: 2021-03-18
    • Source: Internet
    • Author: User
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    Multiple myeloma Multiple myeloma (MM) is a malignant hematological disease derived from mature B cells (plasma cells), which mainly affects the bone marrow.


    Recently, a study published in the journal European Radiology showed that the use of DECT combined with texture analysis explored the correlation between the texture characteristics of myeloma DECT bone marrow imaging and the serum markers related to myeloma activity and the degree of medulla involvement.


    This study retrospectively included 110 patients (63.


    This study retrospectively included 110 patients (63.


    Patients with advanced myeloma have higher first-order characteristics ( p <.


    Table 1 Multiple logistic regression analysis

    Table 1 Multiple logistic regression analysis

    Figure 1 Comparison of the three stages of myeloma according to Durie and Salmon classification.


    Figure 1 Comparison of the three stages of myeloma according to Durie and Salmon classification.


    The CT texture features used in bone marrow imaging have a good correlation with the serological parameters and histology related to myeloma, showing that the tissue structure is more uniform and attenuated as the medulla infiltration increases, so it can be used as a non-invasive Additional imaging biomarkers for sexual assessment of medulla invasion.


    Original source: Original source:

    Christian Philipp Reinert,Eva Krieg,Michael Esser,et al.


    Christian Philipp Reinert,Eva Krieg,Michael Esser,et al.
    Role of computed tomography texture analysis using dual-energy-based bone marrow imaging for multiple myeloma characterization: comparison with histology and established serologic parameters.
    DOI: org/10.
    1007/s00330-020-07320-8">10.
    1007/s00330-020-07320 -8 Christian Philipp Reinert,Eva Krieg,Michael Esser,et al.
    Role of computed tomography texture analysis using dual-energy-based bone marrow imaging for multiple myeloma characterization: comparison with histology and established serologic parameters.
    DOI: org/10.
    1007/s00330-020-07320-8">10.
    1007/s00330-020 -07320-8org/10.
    1007/s00330-020-07320-8"> 10.
    1007/s00330-020-07320-8 Leave a message here
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