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    Home > Active Ingredient News > Antitumor Therapy > Eur Radiol: How is head and neck tumor combined with amyopathy evaluated?

    Eur Radiol: How is head and neck tumor combined with amyopathy evaluated?

    • Last Update: 2021-01-30
    • Source: Internet
    • Author: User
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    Head and neck tumors are the 6th most common tumor in Europe.
    of skeletal muscle mass is a kind of progressive, extensive skeletal muscle abnormality, which is related to clinical adverse consequences.
    currently clinically diagnoses dystrophic disease using the cross-axis area (CSA) indicator of the 3rd cervical vertebrae (C3) horizontal cervical muscle in the CT image of the neck.
    of head and neck tumors were more common, and their weakness, postoperative complications, restrictive toxicity of chemotherapy dose, decreased overall survival and no recurrence were related.
    according to EWGSOP, skeletal muscle mass (SMM) reduction can be diagnosed as less muscle disease.
    , studies usually evaluate and diagnose amyopathy based on the quality of the 3rd cervical vertebral level skeletal muscle on CT.
    However, some patients with head and neck tumors were unable to have a neck CT scan for some reason, while an alternative neck MRI was performed, especially in patients with nasopharyngeal, sinus tumors, and head-to-tongue bone levels, as well as patients with iodine allergies.
    , there are no clear studies showing that the horizontal axis (CSA) in neck CT examination is similar to and similar to all MRI sequence measurements.
    recently, a paper published on Eur Radiol called Skeletal muscle mass and sarcopenia can be made with 1.5-T and 3-T neck MRI scans, in the event no no neck CT scan is performed to demonstrate the possible use of neck MRIs to evaluate skeletal muscle mass for the diagnosis of amyopathy.
    HNC patients from the Prospective Data Biolibrary between November 2014 and November 2018.
    CSAs that measured C3 levels of neck muscle on CT (n s 125) and MRI neck scans (n s 92 on 1.5-T and n s 33 on 3-T).
    the measurements to skeletal muscle index (SMI) and define muscle reduction disorders (SMI -lt;43.2 cm2 / m2).
    Pearson correlation coefficients, Bland-Altman charts, McNemar tests, Cohen's kappa coefficients, and inter-class correlation coefficients (ICC) were evaluated.
    picture. The subjects included in the flowchart study and found that CT and MRI were highly relevant to CSA and SMIs (r s 0.958-0.998, p slt;0.001).
    Bland-Altman graph shows the average margin of error (-0.13-0.44 cm2 / m2).
    there was no statistical difference between CT and MRI in the diagnosis of myocardial dystrophic disease (McNemar, p s 0.5-1.0).
    1.5-T and 3-T are consistent in the diagnosis of myopathy (0.956-0.978 and 0.870-0.933).
    mri's observer ICC is very good.
    , T2-weighted images are best relevant and consistent with CT.
    picture. The results of the C3 horizontal skeletal muscle measurement schematic study showed that skeletal muscle mass and myocardial deficiency could have similar effects in neck CT and 1.5-T or 3-T MRI examinations.
    can be evaluated clinically during treatment, regardless of the method used.
    Screening for changes in skeletal muscle quality written on the back usually relies on neck CT examination, as it is associated with adverse consequences of head and neck tumors, and is an important clinical indicator This study found that C3 level skeletal muscle quality changes evaluated by CT and MRI have a higher consistency When neck CT examination data are missing, neck MRI data can be used to evaluate bone muscle quality changes
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