-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
*For medical professionals only
Recently, esomeprazole has been approved for a new indication for the treatment of gastroesophageal reflux disease
in adolescents aged 12 years and above.
As a proton pump inhibitor, in the treatment of gastroesophageal reflux disease, different types of esomeprazole have different indications!
Erosive reflux esophagitis
▍ Adult domestic usage: oral:
40mg once a day for four weeks
.
For patients with uncured esophagitis or persistent symptoms, additional four weeks of treatment are recommended [1].
Injection: For patients with gastroesophageal reflux disease who cannot be taken orally, it is recommended to inject intravenously or intravenously infusion of this product 20-40mg
once a day.
Patients with reflux esophagitis should be used 40 mg once
daily.
This product should usually be used for a short time (no more than 7 days), and should be converted to oral therapy as soon as possible [2].
▍ Adult FDA Usage: Oral:
Esomeprazole magnesium sustained-release capsules are suitable for short-term treatment (4-8 weeks)
of symptom relief and healing in patients diagnosed with erosive esophagitis after diagnosis.
For patients who do not recover after 4 to 8 weeks of treatment, the addition of esomeprazole magnesium sustained-release capsules for 4 to 8 weeks may be considered [3].
Injections: The recommended adult dose is 20 mg or 40 mg intravenously (at least 3 minutes) or intravenously (10-30 minutes) once daily for up to 10 consecutive days [4].
Long-term maintenance therapy
for patients with esophagitis ▍ Adult domestic usage: oral:
20mg once a day [1].
。
Injection: For patients with gastroesophageal reflux disease who cannot be taken orally, it is recommended to inject intravenously or intravenously 20-40mg of this product once a day, and 20mg should be used once a day for the symptomatic treatment of reflux disease
.
This product should usually be used for a short time (no more than 7 days), and should be converted to oral therapy as soon as possible [2].
▍Adult FDA usage:
Esomeprazole magnesium sustained-release capsules are used for symptom relief and maintenance treatment of erosional esophagitis
.
Controlled studies were no longer than six months [3].
Symptom control
of gastroesophageal reflux disease (GERD) ▍ Adult domestic use: Oral:
Patients without esophagitis 20 mg once
daily.
If symptoms are not controlled after 4 weeks of use, the patient should be further investigated
.
Once symptoms have resolved, subsequent symptom control can be achieved with immediate therapy, i.
e.
, 20 mg orally once daily when needed
.
Subsequent on-demand therapy is not recommended for subsequent symptom control in patients at risk of gastric and duodenal ulcers with NSAIDs [1].
Injection: For patients with gastroesophageal reflux disease who cannot be taken orally, it is recommended to inject intravenously or intravenously infusion of this product 20-40mg once a day, this product should usually be used for a short time (no more than 7 days), once possible, it should be converted to oral treatment [2].
▍Adult FDA Usage:
Esomeprazole magnesium sustained-release capsules are suitable for short-term treatment (4-8 weeks) of heartburn and other symptoms associated with gastroesophageal reflux disease (GERD)
in adults and children over 1 year old.
Recommended dose: 20 mg once daily for 4 weeks [3].
How to adjust the general dose of esomeprazole in patients with liver damage?
What are the symptoms of an overdose of esomeprazole? How to deal with it?
Where to see more common drugs in gastroenterology? Open "Clinical Decision Assistant - Evidence-based Medicine" to search for related disease names/drug names, one click directly! 👇
, Ltd.
, 2016-09-02 [2] Drug information: Nexin, Esomeprazole sodium for injection, AstraZeneca Pharmaceutical Co.
, Ltd.
, 2018-05-25 [3]Drug Information:NEXIUM-esomeprazole magnesium capsule，AstraZeneca Pharmaceuticals LP，11/2020.
[4]Drug Information: NEXIUM I.
V.
-esomeprazole sodium injection，AstraZeneca Pharmaceuticals LP，11/2020.
▼▼▼Click to read the original article to download the App
For more gastroenterology drugs, go to the "Clinical Decision Assistant App"!
Recently, esomeprazole has been approved for a new indication for the treatment of gastroesophageal reflux disease
in adolescents aged 12 years and above.
As a proton pump inhibitor, in the treatment of gastroesophageal reflux disease, different types of esomeprazole have different indications!
Erosive reflux esophagitis
▍ Adult domestic usage: oral:
40mg once a day for four weeks
.
For patients with uncured esophagitis or persistent symptoms, additional four weeks of treatment are recommended [1].
Injection: For patients with gastroesophageal reflux disease who cannot be taken orally, it is recommended to inject intravenously or intravenously infusion of this product 20-40mg
once a day.
Patients with reflux esophagitis should be used 40 mg once
daily.
This product should usually be used for a short time (no more than 7 days), and should be converted to oral therapy as soon as possible [2].
▍ Adult FDA Usage: Oral:
Esomeprazole magnesium sustained-release capsules are suitable for short-term treatment (4-8 weeks)
of symptom relief and healing in patients diagnosed with erosive esophagitis after diagnosis.
For patients who do not recover after 4 to 8 weeks of treatment, the addition of esomeprazole magnesium sustained-release capsules for 4 to 8 weeks may be considered [3].
Injections: The recommended adult dose is 20 mg or 40 mg intravenously (at least 3 minutes) or intravenously (10-30 minutes) once daily for up to 10 consecutive days [4].
Long-term maintenance therapy
for patients with esophagitis ▍ Adult domestic usage: oral:
20mg once a day [1].
。
Injection: For patients with gastroesophageal reflux disease who cannot be taken orally, it is recommended to inject intravenously or intravenously 20-40mg of this product once a day, and 20mg should be used once a day for the symptomatic treatment of reflux disease
.
This product should usually be used for a short time (no more than 7 days), and should be converted to oral therapy as soon as possible [2].
▍Adult FDA usage:
Esomeprazole magnesium sustained-release capsules are used for symptom relief and maintenance treatment of erosional esophagitis
.
Controlled studies were no longer than six months [3].
Symptom control
of gastroesophageal reflux disease (GERD) ▍ Adult domestic use: Oral:
Patients without esophagitis 20 mg once
daily.
If symptoms are not controlled after 4 weeks of use, the patient should be further investigated
.
Once symptoms have resolved, subsequent symptom control can be achieved with immediate therapy, i.
e.
, 20 mg orally once daily when needed
.
Subsequent on-demand therapy is not recommended for subsequent symptom control in patients at risk of gastric and duodenal ulcers with NSAIDs [1].
Injection: For patients with gastroesophageal reflux disease who cannot be taken orally, it is recommended to inject intravenously or intravenously infusion of this product 20-40mg once a day, this product should usually be used for a short time (no more than 7 days), once possible, it should be converted to oral treatment [2].
▍Adult FDA Usage:
Esomeprazole magnesium sustained-release capsules are suitable for short-term treatment (4-8 weeks) of heartburn and other symptoms associated with gastroesophageal reflux disease (GERD)
in adults and children over 1 year old.
Recommended dose: 20 mg once daily for 4 weeks [3].
How to adjust the general dose of esomeprazole in patients with liver damage?
What are the symptoms of an overdose of esomeprazole? How to deal with it?
Where to see more common drugs in gastroenterology? Open "Clinical Decision Assistant - Evidence-based Medicine" to search for related disease names/drug names, one click directly! 👇
Download the Decision Assistant App and check it anytime, anywhere~
References: [1] Drug information: Naxin, Esomeprazole magnesium enteric-coated tablets, AstraZeneca Pharmaceutical Co., Ltd.
, 2016-09-02 [2] Drug information: Nexin, Esomeprazole sodium for injection, AstraZeneca Pharmaceutical Co.
, Ltd.
, 2018-05-25 [3]Drug Information:NEXIUM-esomeprazole magnesium capsule，AstraZeneca Pharmaceuticals LP，11/2020.
[4]Drug Information: NEXIUM I.
V.
-esomeprazole sodium injection，AstraZeneca Pharmaceuticals LP，11/2020.
▼▼▼Click to read the original article to download the App
