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Ionizing radiation is used successfully in cancer therapy to kill tumor cells
Known as store-operated Ca entry (SOCE) activation, the intracellular Ca concentration begins to oscillate at a critical frequency, which in turn leads to the displacement (translocation) of a transcription factor from the cytoplasm into the nucleus
Journal Reference :
Dominique Tandl, Tim Sponagel, Dalia Alansary, Sebastian Fuck, Timo Smit, Stephanie Hehlgans, Burkhard Jakob, Claudia Fournier, Barbara A.