Emodin extracted from traditional Chinese medicine may prevent type 2 DM

The British Journal of pharmacology reported that Dr Leng Ying's research group of Shanghai Institute of medicine, Chinese Academy of Sciences conducted animal experiments on the treatment of diabetes with Chinese herbal medicine in mice The results showed that emodin extracted from rhubarb and Polygonum cuspidatum can reduce the blood sugar and serum insulin content of obese mice, thus reducing their risk of type 2 diabetes The next step will be clinical trials to determine whether emodin can improve insulin resistance in patients with type 2 diabetes or other metabolic diseases, said Leng The research results of Chinese scholars made people realize that emodin may be a potential 11 β - hydroxysteroid dehydrogenase (11 β - HSD1) inhibitor The researchers injected emodin into mice to inhibit 11 β - hydroxysteroid dehydrogenase, thus inhibiting the role of glucocorticoids, and ultimately improve the condition of diabetic patients and reduce the symptoms of insulin resistance This research result has increased people's attention to the special role of 11 β - hydroxysteroid dehydrogenase in the absorption of sugar in diet It is generally believed that when the sugar in the food enters the blood of the human body, the human body will release insulin to remove the excessive sugar in the blood Glucocorticoid can inhibit the action of insulin and lead to the occurrence of diabetes, while 11 β - hydroxysteroid dehydrogenase can enhance the action of glucocorticoid and make the blood sugar of patients higher "We are likely to find a new way to treat type 2 diabetes and other metabolic diseases with Chinese herbal medicine The next step is to further confirm its role through clinical trials and find other new chemical components similar to emodin, and select the effective components suitable for making new drugs," said Leng Ying