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eLife: Young people with genetic risk of mental illness have different brain activity when they sleep

 Last Update: 2022-09-08
 Source: Internet
 Author: User

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Patterns of brain activity during sleep reveal the neurobiological principles behind a genetic disorder called 22q11.

22q11.

"We recently showed that most young people with 22q11.

Electroencephalogram (EEG) is a well-established method

To explore this question at 22q11.

They found significant changes in sleep patterns in the 22q11.

Participants also took part in a 2D object positioning task before going to bed, and they had to remember where the matching cards on the screen were

Finally, the team used a statistical method called "mediation" to estimate the effects

Matt Jones, a professor of neuroscience at the University of Bristol in the UK, concluded: "Our EEG findings together shed light on the complexity of sleep neurophysiology on 22 November and highlight the differences that may be potential biomarkers of DS-associated neurodevelopmental syndromes on 22 November 2nd

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