Effect of Juglans mandshurica extract on the biofilm formation of Candida albicans in vitro
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Last Update: 2014-04-08
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Source: Internet
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Author: User
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Recently, Yu Xiaoli, Wen Ping and Wang Jun, the laboratory of the people's Hospital Affiliated to Jiangsu University, jointly published a paper to study the effect of Juglans mandshurica extract on the formation of Candida albicans biofilm The results showed that the extracts of Juglans mandshurica had a strong inhibitory effect on the biofilm formation of Candida albicans in vitro This paper was published in the Chinese Journal of mycology, Vol 8 (4), 2013 The effect of Juglans mandshurica extract on the biofilm formation and adhesion of Candida albicans was evaluated by XTT reduction The effect of Juglans mandshurica extract on the morphology of Candida albicans biofilm was observed under microscope The minimum inhibitory drug concentrations (smic50, smic90) of 50% and 90% of the biofilm of Candida albicans were 15.2 μ g and 23.4 μ g respectively When the concentration of Juglans mandshurica extract was more than 20 μ g, it could inhibit the cell adhesion 30 μ g Juglans mandshurica extract can completely inhibit the formation of Candida albicans biofilm.
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