Do tea and coffee have an effect on the occurrence of gliomas?

Tea and coffee are two of the most popular drinks in the world.
that tea and coffee intake may be associated with cancer risk.
but little is known about the correlation with the risk of glioma.
in-body studies and animal model experiments have found that the antioxidant and anti-inflammatory effects of nerve-protective compounds in coffee and tea may be of great significance in preventing the development of human gliomas.
because of the relatively low rate of glioma, large case control studies are susceptible to selection bias and potential recall bias.
by David J. Cote of brigham and Women's Hospital in Boston and David J. Cote of Harvard Medical School analyzed the relationship between tea and coffee intake and the risk of glioma.
results were published online in July 2019 in International Journal of Cancer.
Study The study assessed the correlation between tea, coffee and caffeine intake and the development of gliomas in the Women's Nurses' Health Study (NHS), Nurses' Health Research Phase II., and The Male Health Professional Follow-up Study (HPFS).
baseline survey of participants in the three study cohorts and subsequent follow-up surveys every two years, which contained the most up-to-date information.
follow-up rate was more than 90 per cent among participants in the study group.
of tea, coffee and caffeine came from a validated four-year food frequency questionnaire.
primary malignant brain tumor data were obtained through a two-yearly questionnaire self-reporting and then confirmed by a medical records review.
use the Cox proportional risk model to assess the effects of adjusted multivariate intake on the risk of glioma.
study of 6022,741 follow-up patients/year found 554 patients with glioma, of which 256 were in the female nurse health research cohort, 87 in the Nurses' Health Study PHASE II and 211 in the male health professional follow-up study queue.
362 cases of glioblastoma (GBM) in the NHS, NHS II. and HPFS queues of 159, 52 and 151 cases each.
In the combined queue, tea intake was critically negatively correlatored (HR>=0.7; 95% CI, 0.49-1.10; p=0.05) compared to those who drank 1 cup of tea per week> There is no difference between HR-0.7; 95% CI, 0.47-1.18; p-0.11) and men drinking tea >2 cups per day (HR=0.70; 95% CI, 0.30-1.60; p=0.30).
No significant association was observed between caffeine-containing, decaffeination-free or total coffee intake and the risk of glioma;
the authors concluded that tea intake was critically negatively correlate with the risk of glioma.
no significant association was observed between coffee intake and the risk of glioma.
results should be further explored through forward-looking studies.
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