Diab obsity metabol: vitamin D deficiency is associated with the risk of gestational diabetes

May 29, 2019 / BIOON / - a study recently published in the Journal of diabetes, obsity and metabolism shows that if pregnant women lack vitamin D as early as the first three months of pregnancy, it will increase the risk of gestational diabetes mellitus (GDM) Jin Xia and colleagues from Richard M Fairbanks School of public health at Indiana University used data from fatal growth studies singleton cohort to prospectively study the relationship between vitamin D status and GDM risk in the first to second trimester of pregnancy The levels of 25 hydroxyvitamin D2, D3 and vitamin D-binding protein were measured in 107 pregnant women with GDM and 214 control participants at weeks 10-14, 15-26, 23-31 and 33-39 of gestation Image source: http://cn.bing.com researchers looked at the threshold effect of the relationship between vitamin D biomarkers and GDM risk Vitamin D deficiency (< 50 nmol / L) was associated with a 2.82-fold increase in GDM risk at 10-14 weeks of gestation The risk of GDM was 4.46 times higher in women who continued to lack vitamin D between 10 and 14 weeks of gestation and 15 to 26 weeks of gestation than in women who did not lack vitamin D for a long time "The assessment of vitamin D status in early pregnancy may have important clinical significance and value in improving risk stratification and developing effective interventions to prevent GDM," the authors write "Reference: Jin Xia et al Vitamin D status during precedence and the risk of gestational dialogues mellitus: a longitudinal study in a multi-channel cohort Dialogues, objectivity and metabolism Doi: https://doi.org/10.1111/dom.13748