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On October 20, the reporter learned from an interview with Professor Li Aitao of the School of Life Sciences of Hubei University and the State Key Laboratory of Biocatalysis and Enzyme Engineering jointly established by the province and the ministry that Li Aitao's research team has made a major breakthrough in the field of nylon monomer preparation, breaking the existing Due to the high pollution and high energy consumption caused by the industrial synthesis of nylon monomers, a new method is found for the preparation of nylon monomers
.
The researchers designed a new artificial biosynthesis pathway for nylon monomers by designing a microbial flora catalytic system
.
"Nylon 66 is prepared by the condensation of adipic acid and hexamethylene diamine, and adipic acid is the main monomer.
In traditional industries, its synthesis mainly relies on a multi-step chemical oxidation process with high pollution and high energy consumption
.
In order to meet the above challenges, Li Aitao's team designed an artificial biosynthesis system based on the previous accumulation in biocatalysis, which can catalyze the synthesis of cyclohexane to nylon 66 monomer adipic acid
.
"In addition, using the rationally designed Escherichia coli microbiome as a catalyst, a variety of cycloalkanes or cycloalkanols (C5~C8) can be synthesized to obtain different α,ω-dicarboxylic acids, which fully proves the generality of this method.
Finally
, the whole biotransformation reaction was amplified in the fermenter, and the production of adipic acid was successfully realized.
Nylon, as a very widely used synthetic fiber, is used in many important fields related to the national economy and people's livelihood
.
