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    Home > Active Ingredient News > Drugs Articles > Development and performance characteristics of single-use bioprocessing

    Development and performance characteristics of single-use bioprocessing

    • Last Update: 2022-08-20
    • Source: Internet
    • Author: User
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    Scalable single-use bioprocessing product line to include pilot (3L), pilot scale (50L and 200L), and clinical and commercial scale (1,000L and 2,000L) stirred tank bioreactors to support early process development through Optimized cell culture for commercial production
    .

    Mobius bioreactors can be flexibly configured to meet your fed-batch or perfusion application needs with software, hardware, and single-use components, ensuring that small-scale flexible operations can be converted to full-scale production
    .

    Disposable biotechnology product features: 1.
    Innovative design of main bag + double satellite bag (real RNase-/DNase-free bag inspection); 2.
    The material/production environment of the main bag and satellite bag is exactly the same; 3.
    Satellite bag- 1 (QC release) is used for RNase detection before product release; 4.
    Satellite bag-2 (customer sample) is used for sample review at the customer; Liquid bag + reaction bag + cell bag, etc.
    ) 6.
    High-standard production environment control and monthly RNase detection The one-time biological process is mainly composed of imported 9101 membrane, stirring paddle, feeding port, liquid inlet pipe, liquid outlet pipe, temperature electrode interface, etc.
    Accessories composition
    .

    The magnetic stirring paddle is built into the bag body, and two types of suspended magnetic stirring paddles and bearing-connected stirring paddles can be customized according to customer needs
    .

    The bearing-type stirring paddle is composed of the central shaft of the bottom tray, ceramic bearings and paddles, and the paddles will not contact with the bag body or other accessories when working
    .

    The magnetic levitation type is composed of a bottom concave chassis and paddles
    .

    The magnetic levitation type adopts superconducting drive.
    After the magnetic field is formed, the stirring paddle will be suspended and rotated for stirring and mixing, without bearing connection and without contact with the bag body or other accessories, nor any friction with other parts
    .

    The 3D disposable magnetic stirring bag needs to be supported by a three-dimensional container with a fixed shape.
    Generally, there are two types of support containers: square and cylindrical
    .

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