Day experts use mouse embryonic stem cells to build red line progenitor cell lines
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Last Update: 2020-07-04
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Source: Internet
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Author: User
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the Japan Institute of Science and Science has announced the establishment of a red line progenitor cell line using embryonic stem cells in laboratory mice, and confirmed that the differentiation of red blood cells from this progenitor cell line can effectively treat acute anemia in laboratory miceThe Institute of Science and Technology said that through blood transfusion to supplement red blood cells difficult to prevent infection with hepatitis and otherdiseases, people may urgently need a large number of synthetic red blood cells in the future technologyRed blood cells are an important blood component of transporting oxygen, red blood cells themselves can not multiply, in the human body red blood cells rely on their protocellular proliferation,differentiationTherefore,,to make a large number of red blood cells,must proliferate a large number of progenitor cells of red blood cellsOnce theof the red line progenitor cell line is established,can proliferate the progenitor cells to the desired amount at any time in the test tubeUsing eight experimental mouse embryonic stem cell lines, researchers at the Institute of Science and Chemical Research added nourishing cells and proliferative factors, and conducted a total of 63 differentiation-induced experiments , resulting in five blood progenitor cell lines, three of which were red line progeny cell lines The researchers then gave the mice severe acute anemia and transplanted the red line progenitor cell line into their bodies As a result, seven of the eight laboratory mice who received the transplant survived, while seven of the eight diseased mice without the transplanted red line ancestral cell line died Researchers are currently testing new technologies that they hope will use to develop safe human red line progenitor cell lines
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