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Our skin forms the physical boundary between us and the outside world, but it still holds an alarming number of secrets
.
In a study published this month in Cell Reports, a team of researchers led by the Institute of Industrial Science, the University of Tokyo revealed that sensory neurons in human skin play an important role
in pigmentation.
The pigmentation on our skin is partly caused by a group of substances called melanin, which are produced
by skin cells called melanocytes.
"There is growing evidence of the possibility that the interaction between neurons and melanocytes plays a number of key roles in human skin," said
Siu Yu Chow, lead author of the study.
In their study, the researchers explored the relationship between sensory neurons and melanocytes and found that in skin-tone patch tissue, there was greater
contact between them than in control tissue.
"In addition, we also found proteins secreted by sensory neurons, including the rejection guiding molecule B (RGMB)," explains senior author Yoshiho Ikeuchi
.
"Our findings underscore the importance of sensory neurons for skin pigmentation and physiology," Chow said
.
Pigmentation disorders, including skin pigmentation, are common and can cause psychosocial problems; They are also often associated with health problems such as neurodermatomy (diseases that affect the nervous system and skin) and melanoma
.
Siu Yu A.
