-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
According to a new study, the longer you go to school, the higher the risk of myopia
, due to the presence of five genetic variants.
, due to the presence of five genetic variants.
A new study published in the journal PLOS Genetics by a team led by Jeremy Guggenheim at Cardiff University found that five genetic variants significantly increase a person's risk of
myopia as they spend more time in school.
Myopia is a common eye disease that can cause irreversible visual impairment in older adults, usually developing
in childhood.
This condition is thought to be caused by a combination of genetics, limited time spent outdoors and long-term education
.
Genetic studies have identified more than 450 genetic variants associated with an increased risk of myopia, but few studies have shown that this variant increases the risk
of myopia, especially in people with associated lifestyle factors.
For the new study, the researchers used genetic and health data
from more than 340,000 participants of European ancestry.
They conducted a genome-wide study to identify genetic variants
that make people more likely to develop myopia when combined with intensive education.
The study found five genetic variants that gradually increased the risk of myopia as individuals spent more time in school, especially for those with a college education
.
Three of the variants were previously unknown, while two were found in studies in East Asian populations, where about 80 percent of children develop myopia
.
In contrast, about 30% of children in Western countries suffer from myopia
.
The researchers say the findings provide new insights into the biological pathways that lead to myopia, but more research is needed to understand how these pathways interact with lifestyle factors that lead to this
.
Guggenheim added: "In addition to requiring glasses or contact lenses, myopia is also a leading cause of
uncorrectable visual impairment.
Building on our previous research on education and myopia, the new study identifies 5 genes associated with the development of myopia, whose effects amplify
with years of schooling.
”
References "Education interacts with genetic variants near GJD2, RBFOX1, LAMA2, KCNQ5 and LRRC4C to confer susceptibility to myopia" by Rosie Clark, Alfred Pozarickij, Pirro G.
Hysi, Kyoko Ohno-Matsui, Cathy Williams, Jeremy A.
Guggenheim and the UK Biobank Eye and Vision Consortium, 17 November 2022, PLOS Genetics.
