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Today, China’s National Food and Drug Administration (NMPA) drug approval certificate pending information shows that the KIT and PDGFRA mutant kinase inhibitor avapritinib (previously used Chinese name: apotinib) declared by CStone Pharmaceuticals is already available China was approved.
It is reported that the approved indication for avatinib this time is: for the treatment of unresectable or metastatic gastrointestinal stromal tumor (GIST) adult patients with PDGFRA exon 18 mutation (including PDGFRA D842V mutation).
Avatinib is a highly specific KIT and PDGFRA mutant kinase inhibitor developed by Blueprint Medicines.