COVID-19 vaccination strategy: when is one dose better than two?

In many parts of the world, the supply of COVID-19 vaccine continues to lag behind demand

In "Chaos" by "AIP Publishing", researchers from Frankfurt School of Finance and Management and University of California, Los Angeles explained the conditions under which the "first priority" vaccine campaign is most effective in preventing the spread of the COVID-19 virus

The main first campaign is not to recommend that people get only one dose of the vaccine

From an immunological point of view, the best stimulation program is always better

Scientists simulated the spread of COVID-19 with a model of susceptibility, exposure, infection, recovery, and death

Each compartment is further divided to consider unvaccinated, partially vaccinated, and fully vaccinated individuals

Author Jan Nagler said: "We have a large degree of uncertainty about the parameters of COVID-19

The research team found that the decline in vaccine usage was a key factor in this decision

However, if the attenuation rate after a single injection is closer to the attenuation rate after two injections, the vaccine strategy will change

The author of the study, Lucas B?ttcher, said: "Our results show that a better estimate of the rate of immune weakening is important for determining whether the primary priority program is more effective than the primary booster vaccine

As the scientific community gathers more data on COVID-19 vaccination, scientists hope that this model will provide more information to public health experts and politicians who must decide to support or oppose a vaccination protocol