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HONG KONG, China, Aug. 27 (Xinhua) -- Hong Kong, China, has reported the world's first case of re-infection of the new crown virus, a 33-year-old man who was diagnosed with the new crown at the end of March recovered from treatment and was discharged from hospital after returning from a trip to Europe in August.
repeated infections after recovery mean that even if the new crown vaccine is officially put into use, it will not really beat the outbreak? What does this case bring to the prevention and control of the new crown epidemic? Experts believe that the case of secondary infection of the new coronavirus is not a routine event, there is no need to worry too much, the significance of the case is to help researchers better understand the body's immune response to the new coronavirus.
from previously reported cases of Fuyang, the newly reported cases of re-infection provide for the first time conclusive evidence that patients with new coronary rehabilitation may re-infect.
" Fuyang" refers to the new crown patients reached the discharge standard and then appeared nucleic acid positive.
experts believe that such cases with "re-screening" description may be more accurate, the patient's body virus has not really eliminated, although the upper respiratory swab sampling can not detect the virus, but the virus is still present in the body.
addition, the lack of sensitivity of nucleic acid testing reagents may also lead to "false negative" results.
In a new study published in the 25th issue of clinical infectious diseases, the department of microbiology at the University of Hong Kong and the Queen Mary Hospital in Hong Kong reported that the second infection of the re-infected person occurred on the 142nd day after the first infection, comparing the genomes of the two infections with the new coronavirus genomes, which belong to different branches of the new coronavirus spectrum, have more than 20 different nucleotides, and there are amino acid differences in nine proteins, confirming that the patient is re-infected, rather than the first infection.
previous studies have shown that antibody levels in the body drop rapidly after the new coronavirus infection has healed.
chinese team reported in June in the British journal Nature Medicine that their study in Chongqing found that about 90 percent of cases had a reduction in total antibody levels by more than 70 percent in the two months after discharge.
researchers believe that new coronavirus infections may be infected again when they recover.
newly reported cases of repeated infection confirm these findings and suggest that new coronavirus infections may not be immunized for life.
does this mean that even if the new crown vaccine is put into service, it won't really beat the epidemic? Experts say secondary infections of the new coronavirus are extremely rare at the population level and will not have a significant impact on immunization through vaccination.
World Health Organization spokeswoman Margaret Harris said on the 25th, the world's more than 23 million newly confirmed cases of secondary infection, indicating that this is not a "normal event", otherwise we will see more cases.
A report published on the website of the American journal Science quoted Angela Rasmussen, a virologist at Columbia University, as saying that the second infection may be a rare case of a first infection that does not produce a good immune response, "I don't think it has a significant impact on vaccines and immunity."
have also observed secondary infections in studies of other coronavirus.
the report quoted Charlotte Holdcroft, a virologist at the University of Cambridge, as saying that tests conducted in the UK in the 1980s showed that some people could be man-madely reinfested a year after contracting the coronavirus that causes the common cold.
most virulism scholars expect a similar situation to occur with new coronavirus infections, which is more a question of how long the interval will occur than whether it will occur, Mr. Holdercroft said.
in the UK also showed that participants who did not respond well to the body's immune response at the time of the first infection were more likely to be second-time infected.
, deputy dean of the Surifo School of Public Health at the National University of Singapore, told the media it was not clear how common it was for patients with the new crown to be repeatedly infected with the virus, but it was certain that re-infection within six months was very rare.
the body's immunity to other respiratory viruses, such as influenza, is known to weaken over time, so it is recommended that high-risk populations be vaccinated every year.
researchers also saw a positive side in secondary infections.
the patient was asymptomatic when he beed out for a second infection, according to the researchers.
, a viral immunologist at Oregon Health Sciences University, told Science that this suggests that even if a patient is infected with a different strain than the first one, he is protected by the immune system. " (The patient's) secondary infection is asymptomatic, indicating that the immune system's ability to fight re-infection is not strong enough to protect the body from the disease,"
Aoshi Iwazaki, a professor of immunology at Yale University, said in a comment on social media.
" Iwasaki also stressed that because of the presence of secondary infections, the realization of so-called "group immunity" through natural infections is unlikely to eliminate the new coronavirus, the only safe and effective way to achieve group immunization is vaccination.
(Participating journalists: Wang Lili, Zhang Jiawei)