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    Home > Active Ingredient News > Immunology News > "Coke bottle sign", what does this sign suggest?

    "Coke bottle sign", what does this sign suggest?

    • Last Update: 2022-02-19
    • Source: Internet
    • Author: User
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    cola bottle sign

    Coke bottle sign Coke bottle sign

    Refers to the appearance of orbital muscles in thyroid eye disease on axial scan.


    Refers to the appearance of orbital muscles in thyroid eye disease on axial scan.


    Muscle thickening follows a slow pattern "I'MSLOW"


    The nature of muscle enlargement is very important and is one of the main features that distinguish it from orbital inflammatory pseudotumors.



    The patient (40-year-old female, Graves disease, decreased visual acuity) had bilateral bulging eyes, enlarged medial, superior and inferior rectus muscle belly, and increased T2 signal 

    The patient (40-year-old female, Graves disease, decreased visual acuity) had bilateral bulging eyes, enlarged medial, superior and inferior rectus muscle belly, and increased T2 signal 

    Patient (middle-aged female)

    Patient (middle-aged female)

    Hyperthyroidism exophthalmos is one of the most common orbital diseases in adults and is an autoimmune disease


    Hyperthyroidism exophthalmos is one of the most common orbital diseases in adults and is an autoimmune disease


    In the acute phase, the main primary changes are inflammation, volume effects due to extraocular muscle hypertrophy and increased orbital fat volume, and restriction of movement resulting from muscle changes


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    Differential diagnosis : myositis inflammatory pseudotumor

    Differential diagnosis : Myositis-type inflammatory pseudotumor diagnosis

    Orbital inflammatory pseudotumor (orbital pseudotumor) or idiopathic orbital inflammation, most scholars believe that inflammatory pseudotumor is an immunoreactive disease


    Orbital inflammatory pseudotumor (orbital pseudotumor) or idiopathic orbital inflammation, most scholars believe that inflammatory pseudotumor is an immunoreactive disease


    Inflammation manifests as acute, subacute, or chronic, alternating unilaterally or bilaterally


     Myositis type manifests as thickening of one or several extraocular muscles, more common superior rectus and medial rectus muscles, typically thickening of both tendon and muscle belly, with blurry and irregular edges




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